Parkinson’s Disease Early diagnosis and treatment
Parkinson's Disease Diagnosis and Treatment Parkinson’s is a very much associated with a progressive loss of dopamine neuron. These are striatonigral neurons and those neurons release dopamine through allow us to move normally. It turns out that person who lose about 50% to 60% of these neuron and dopamine and the striatum would be reduced to about 50% to 60% before the onset of motor signs of Parkinson’s disease occur. We still don’t have to-date a biological marker of Parkinson’s disease. There are imaging technologies that are available in research sites and some of these may be available on a more widespread basis soon, but one can use either beta-CIT or other ligand and SPECT imaging where these ligand binds to dopamine transporters and the dopamine nerve terminals and it gives you an index of remaining dopamine neurons, so this is a sort of representation from the early Parkinson’s disease. So Parkinson’s Disease then still remains a cli...